Hello earlyriser81, the answer to your question is NO and YES. The real information you are seeking is Why Yes and why No. In the beginning of your leader, the BUTT End, or the Thick end which is closest to the fly line you need a line that will transfer the energy that is stored up in your loop into to the leader and down to the fly. If you use regular Monofiliment line it will be to limp causing you to loose energy. Most will suggest that you use what is called Hard Mono. Maxima is one manufacturer of such lines. Then as you step down in your leaders size your progression would ultimately lead you to your tippet. The hard mono will retain and transfer the energy from the rod, to the line/loop to the leader to the tippet very nicely for you. You will want to switch over to the mono about mid way down your tapering of the leader so the line becomes (Softer) and won't hit the water with as much impact. At the end of your leader as you are already aware of is your tippet. You can use regular line here but I wouldn't unless I'm fishing for bass or panfish. The reason is the fly tippet material is made to specific and exacting diameters to ensure that the line is smooth and consistent. Typically you will find that regular mono is not the same diameter through and through. I know I have put it to the micrometer before. You will also find that the tippet manufactures generally have a thinner diameter which still achieves the same pound test that a regular fishing line has which will also not be as spooky to the fish and will land softer on the surface of the water. Now this is not gospel and if you don't want to you can do as you like. I know many people who are happy using regular mono for their fly fishing. I will tell you though they are not in the top 10% of fly fisherman that I know. One last thing, it is generally less expensive to by a small spool of tippet material in 3 or 4 different sizes than it is to purchase 3 or 4 complete spools of the different pound test lines that you will use for different situations as time goes by and it is easier to carry a small spool of tippet as well. I hope this helps you out and guides you in the right direction. Tight lines