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I know the basics of the disease but could someone give me some specifics?
Concerned Hunter
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wwwnc.cdc.gov/eid/article/18/3/11-0685_article.htm
Tuesday, April 02, 2013
IMPORTANT: Cervid Industry and State Veterinarians on Rewriting Chronic Wasting Disease Rule
chronic-wasting-disease.blogspot.com/2013/04/important-cervid-industry-and-state.html
Friday, November 09, 2012
*** Chronic Wasting Disease CWD in cervidae and transmission to other species
chronic-wasting-disease.blogspot.com/2012/11/chronic-wasting-disease-cwd-in-cervidae.html
Sunday, November 11, 2012
*** Susceptibilities of Nonhuman Primates to Chronic Wasting Disease November 2012
chronic-wasting-disease.blogspot.com/2012/11/susceptibilities-of-nonhuman-primates.html
Friday, December 14, 2012
Susceptibility Chronic Wasting Disease (CWD) in wild cervids to Humans 2005 - December 14, 2012
chronic-wasting-disease.blogspot.com/2012/12/susceptibility-chronic-wasting-disease.html
The chances of a person or domestic animal contracting CWD are “extremely remote,” Richards said. The possibility can’t be ruled out, however. “One could look at it like a game of chance,” he explained. “The odds (of infection) increase over time because of repeated exposure. That’s one of the downsides of having CWD in free-ranging herds: We’ve got this infectious agent out there that we can never say never to in terms of (infecting) people and domestic livestock.”
www.avma.org/News/JAVMANews/Pages/121201a.aspx
The potential impact of prion diseases on human health was greatly magnified by the recognition that interspecies transfer of BSE to humans by beef ingestion resulted in vCJD. While changes in animal feed constituents and slaughter practices appear to have curtailed vCJD, there is concern that CWD of free-ranging deer and elk in the U.S. might also cross the species barrier. Thus, consuming venison could be a source of human prion disease. Whether BSE and CWD represent interspecies scrapie transfer or are newly arisen prion diseases is unknown. Therefore, the possibility of transmission of prion disease through other food animals cannot be ruled out. There is evidence that vCJD can be transmitted through blood transfusion. There is likely a pool of unknown size of asymptomatic individuals infected with vCJD, and there may be asymptomatic individuals infected with the CWD equivalent. These circumstances represent a potential threat to blood, blood products, and plasma supplies.
cdmrp.army.mil/prevfunded/nprp/NPRP_Summit_Final_Report.pdf
Tuesday, December 18, 2012
A Growing Threat How deer breeding could put public trust wildlife at risk
chronic-wasting-disease.blogspot.com/2012/12/a-growing-threat-how-deer-breeding.html
chronic-wasting-disease.blogspot.com/
kind regards, terry
CWD is a TSE (transmissible spongiform encephilopathy). TSE's behave very differently from the viral, bacterial and parasitic diseases we are all familiar with. The infectious agent is a thing called a "prion", a mutated protein. Some TSE's are contagious, some are not. They are usually species specific.
CWD is a contagious TSE of cervids (deer, elk, caribou, moose). CWD prions are shed by infected cervids via feces, urine and saliva, and eventually by their carcass.
CWD prions congregate most densely in brain, nervous tissue, and the lymph system. Prions persist in the soil, remaining infectious for 25 years or more.
CWD is 100% fatal, killing in a way that side-steps the immune system. There is no such thing as immunity. Gestation period is 18-24 months before visible symptoms appear. Infected animals can shed the infectious prions during that gestation period, even though they appear healthy. Once symptoms appear, indicating the prions have begun damaging brain tissue, the animal dies within 4-6 weeks.
In the early years when CWD becomes established in an area, transmission is primarily by direct contact (nose-nose contact, social grooming, etc) but as the prion load builds up in the soil, the environment itself increases as a vector of the disease.
CWD is more persistent than virulent. It is not cyclic or dependent on variable conditions, except for herd density. It doesn't flare up and infect the whole herd at once. Once established in a system it slowly increases in prevalence year by year. Management techniques can slow but not stop or reverse the spread of the disease. In one area of Wyoming the mule deer herd went from 15% to 57% infected from 2001 to 2011. The population dropped by about half in that period. The infection rate continues to rise, and the population continues to drop. Researchers do not know where it will end.
No dependable live-test for CWD has been developed yet. Only dead deer can be reliably tested, even for confined cervids.
TSE's tend to be species-specific, and the "inter-species barrier" can be quite high. But it is not absolute. A TSE jumped from cattle to humans in a few instances with mad-cow disease. And cervids got it from somewhere, the best guess being scrapie (a TSE of sheep). CWD appears to have a very strong inter-species transmission barrier, but it is still early days. No researcher will say with certainty that it will never jump to livestock or even humans.
It's a bit Missouri-centric, but you can find more at stevejones.cc/cwd (a non-commercial info site with no ads and no signup... just info)
Post a Reply
wwwnc.cdc.gov/eid/article/18/3/11-0685_article.htm
Tuesday, April 02, 2013
IMPORTANT: Cervid Industry and State Veterinarians on Rewriting Chronic Wasting Disease Rule
chronic-wasting-disease.blogspot.com/2013/04/important-cervid-industry-and-state.html
Friday, November 09, 2012
*** Chronic Wasting Disease CWD in cervidae and transmission to other species
chronic-wasting-disease.blogspot.com/2012/11/chronic-wasting-disease-cwd-in-cervidae.html
Sunday, November 11, 2012
*** Susceptibilities of Nonhuman Primates to Chronic Wasting Disease November 2012
chronic-wasting-disease.blogspot.com/2012/11/susceptibilities-of-nonhuman-primates.html
Friday, December 14, 2012
Susceptibility Chronic Wasting Disease (CWD) in wild cervids to Humans 2005 - December 14, 2012
chronic-wasting-disease.blogspot.com/2012/12/susceptibility-chronic-wasting-disease.html
The chances of a person or domestic animal contracting CWD are “extremely remote,” Richards said. The possibility can’t be ruled out, however. “One could look at it like a game of chance,” he explained. “The odds (of infection) increase over time because of repeated exposure. That’s one of the downsides of having CWD in free-ranging herds: We’ve got this infectious agent out there that we can never say never to in terms of (infecting) people and domestic livestock.”
www.avma.org/News/JAVMANews/Pages/121201a.aspx
The potential impact of prion diseases on human health was greatly magnified by the recognition that interspecies transfer of BSE to humans by beef ingestion resulted in vCJD. While changes in animal feed constituents and slaughter practices appear to have curtailed vCJD, there is concern that CWD of free-ranging deer and elk in the U.S. might also cross the species barrier. Thus, consuming venison could be a source of human prion disease. Whether BSE and CWD represent interspecies scrapie transfer or are newly arisen prion diseases is unknown. Therefore, the possibility of transmission of prion disease through other food animals cannot be ruled out. There is evidence that vCJD can be transmitted through blood transfusion. There is likely a pool of unknown size of asymptomatic individuals infected with vCJD, and there may be asymptomatic individuals infected with the CWD equivalent. These circumstances represent a potential threat to blood, blood products, and plasma supplies.
cdmrp.army.mil/prevfunded/nprp/NPRP_Summit_Final_Report.pdf
Tuesday, December 18, 2012
A Growing Threat How deer breeding could put public trust wildlife at risk
chronic-wasting-disease.blogspot.com/2012/12/a-growing-threat-how-deer-breeding.html
chronic-wasting-disease.blogspot.com/
kind regards, terry
CWD is a TSE (transmissible spongiform encephilopathy). TSE's behave very differently from the viral, bacterial and parasitic diseases we are all familiar with. The infectious agent is a thing called a "prion", a mutated protein. Some TSE's are contagious, some are not. They are usually species specific.
CWD is a contagious TSE of cervids (deer, elk, caribou, moose). CWD prions are shed by infected cervids via feces, urine and saliva, and eventually by their carcass.
CWD prions congregate most densely in brain, nervous tissue, and the lymph system. Prions persist in the soil, remaining infectious for 25 years or more.
CWD is 100% fatal, killing in a way that side-steps the immune system. There is no such thing as immunity. Gestation period is 18-24 months before visible symptoms appear. Infected animals can shed the infectious prions during that gestation period, even though they appear healthy. Once symptoms appear, indicating the prions have begun damaging brain tissue, the animal dies within 4-6 weeks.
In the early years when CWD becomes established in an area, transmission is primarily by direct contact (nose-nose contact, social grooming, etc) but as the prion load builds up in the soil, the environment itself increases as a vector of the disease.
CWD is more persistent than virulent. It is not cyclic or dependent on variable conditions, except for herd density. It doesn't flare up and infect the whole herd at once. Once established in a system it slowly increases in prevalence year by year. Management techniques can slow but not stop or reverse the spread of the disease. In one area of Wyoming the mule deer herd went from 15% to 57% infected from 2001 to 2011. The population dropped by about half in that period. The infection rate continues to rise, and the population continues to drop. Researchers do not know where it will end.
No dependable live-test for CWD has been developed yet. Only dead deer can be reliably tested, even for confined cervids.
TSE's tend to be species-specific, and the "inter-species barrier" can be quite high. But it is not absolute. A TSE jumped from cattle to humans in a few instances with mad-cow disease. And cervids got it from somewhere, the best guess being scrapie (a TSE of sheep). CWD appears to have a very strong inter-species transmission barrier, but it is still early days. No researcher will say with certainty that it will never jump to livestock or even humans.
It's a bit Missouri-centric, but you can find more at stevejones.cc/cwd (a non-commercial info site with no ads and no signup... just info)
Post a Reply