I'm out here in Northern Az.. I do most of my hunting in some canyon lands where my shots will be from 200-300 yds.. I usually sight in my Winchester Model 70 cal. 270 150 gr. bullet where my groupings are about 2-3 inches high @ 100 yds.. So I'm good from 100-350+ yds.. Hope this helps.

I live in Northwestern Oregon, and my .25-.30 caliber rifles are zeroed an inch high at 100 yards. My varmint rifles are zeroed depending on the site where I use them. The .223 is precisely zeroed at 100 yds., and my .22-250 is zeroed for 200 yds at Tri-County Gun Club. >95% of my shooting is done at 50 to 200 yards. It is very rare that I'm presented with a varmint shot at a distance greater than 200, and the dense woods usually limit my shots on deer to 50-75 yards. I practice accordingly, and two of my rifles are equipped with aperture (receiver) sights for that reason.

Zero to your liking at 100yds, then set a target at 25 and shoot it to see where it prints. Keep a note of that 25 yd shot ( or keep he target) so the next time you need to check your zero, you can do it with a 25 yd shot. I can make a 25 yd shot in my back yard, but must load up guns & gear 7 travel a few miles to shoot at 100 yds.