.270. Don't be fooled by the modest bullet weights and (by today's standards) less than screaming velocity; there is very little the .270 can't handle with dispatch. Along with the .280, it's probably the best combination of light recoil and major power that we have. It comes in 130-, 140-, and 150-grain loadings, and the type of bullet is much more important than the bullet weight. Given the right slugs, it will flatten any deer that ever walked and much bigger game as well.