While no expert, I on the other hand have played around with the little furry creatures a lot the past four or five years. Throwing them in pretty much every body of water I can think of for plenty of different species. Many times I abandon the “rules” on how you’re supposed to use mice. One thing for certain I can tell you is that they work many, many times when I thought there was no way they would, and that is a lot of fun. In bright sunlight, on two weights, in a tiny stream, for ten inch cutthroats. Situations like that… I’ve used mice on almost every sized river, creek, and trickle of water with success on all of them.