You can shoot hundreds of black bears and hundreds of elk with a .243, and if you choose your bullet wisely and place your shots judiciously, nearly all of them will drop either in their tracks or after a short run. Some will not. This is because wild animals—all species, not just elk and black bear—act unpredictably when hit by bullets. Almost all of them will at least flinch, but some don’t. I’ve heard that deer will never run uphill when shot, but I once hit a whitetail doe who bolted up a steep slope and ran right into a tree. I’ve seen a deer shot through the lungs with a .358 Winchester (250-grain Silvertip, if you must pry) who ignored the shot, dropped his head and continued feeding. Then, after a while, he keeled over. I’ve seen a puku, a tough African antelope about the weight of a big mule deer, hit smack in the shoulder with a 250-grain Nosler Partition from a .338 and stand there, absolutely unmoving, for probably five minutes, and then drop in his tracks.